Gene Cluster: SQSTM1

Organism: Homo sapiens

Synonymous: A170|OSIL|PDB3|ZIP3|p60|p62|p62B

sequestosome 1

Link to Entrez Gene

Map: 5q35

GO:0005515 protein binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006915 apoptosis
GO:0006950 response to stress
GO:0006955 immune response
GO:0007242 intracellular signaling cascade
GO:0008104 protein localization
GO:0008270 zinc ion binding
GO:0016197 endosome transport
GO:0019901 protein kinase binding
GO:0030154 cell differentiation
GO:0030971 receptor tyrosine kinase binding
GO:0042169 SH2 domain binding
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043130 ubiquitin binding
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046872 metal ion binding

Reference Sequence: NM_003900.3

2868bp CDS 41..1363

Homologous cDNA sequence in the JCRB Genebank

SQSTM1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee