Gene Cluster: TIMP3

Organism: Homo sapiens

Synonymous: HSMRK222|K222|K222TA2|SFD

TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)

Link to Entrez Gene

Map: 22q12.1-q13.2|22q12.3

GO:0003674 molecular_function
GO:0004857 enzyme inhibitor activity
GO:0005515 protein binding
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007601 visual perception
GO:0008191 metalloendopeptidase inhibitor activity
GO:0008624 induction of apoptosis by extracellular signals
GO:0050896 response to stimulus

Reference Sequence: NM_000362.4

5496bp CDS 1187..1822

Homologous cDNA sequence in the JCRB Genebank

TIMP3 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee