Gene Cluster: TGFBR1

Organism: Homo sapiens

Synonymous: AAT5|ACVRLK4|ALK-5|ALK5|SKR4|TGFR-1

transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)

Map: 9q22

GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0004872 receptor activity
GO:0005024 transforming growth factor beta receptor activity
GO:0005025 transforming growth factor beta receptor activity, type I
GO:0005114 type II transforming growth factor beta receptor binding
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral to plasma membrane
GO:0006468 protein amino acid phosphorylation
GO:0007165 signal transduction
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007181 transforming growth factor beta receptor complex assembly
GO:0007507 heart development
GO:0008284 positive regulation of cell proliferation
GO:0008354 germ cell migration
GO:0009790 embryonic development
GO:0009952 anterior/posterior pattern formation
GO:0016020 membrane
GO:0016740 transferase activity
GO:0030145 manganese ion binding
GO:0030199 collagen fibril organization
GO:0043066 negative regulation of apoptosis
GO:0043235 receptor complex
GO:0045449 regulation of transcription
GO:0046332 SMAD binding
GO:0048538 thymus development
GO:0048663 neuron fate commitment
GO:0048705 skeletal system morphogenesis
GO:0048844 artery morphogenesis
GO:0050431 transforming growth factor beta binding
GO:0060017 parathyroid gland development
GO:0060021 palate development
GO:0060037 pharyngeal system development

Reference Sequence: NM_004612.2

6475bp CDS 77..1588

TGFBR1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee