Gene Cluster: BCL3

Organism: Homo sapiens

Synonymous: BCL4|D19S37

B-cell CLL/lymphoma 3

Link to Entrez Gene

Map: 19q13.1-q13.2

GO:0000060 protein import into nucleus, translocation
GO:0002268 follicular dendritic cell differentiation
GO:0002315 marginal zone B cell differentiation
GO:0002455 humoral immune response mediated by circulating immunoglobulin
GO:0002467 germinal center formation
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-dependent
GO:0006974 response to DNA damage stimulus
GO:0007249 I-kappaB kinase/NF-kappaB cascade
GO:0008134 transcription factor binding
GO:0009615 response to virus
GO:0010225 response to UV-C
GO:0016481 negative regulation of transcription
GO:0019730 antimicrobial humoral response
GO:0030198 extracellular matrix organization
GO:0030528 transcription regulator activity
GO:0030674 protein binding, bridging
GO:0032729 positive regulation of interferon-gamma production
GO:0032996 Bcl3-Bcl10 complex
GO:0033257 Bcl3/NF-kappaB2 complex
GO:0042088 T-helper 1 type immune response
GO:0042345 regulation of NF-kappaB import into nucleus
GO:0042536 negative regulation of tumor necrosis factor biosynthetic process
GO:0042742 defense response to bacterium
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0042832 defense response to protozoan
GO:0043066 negative regulation of apoptosis
GO:0045064 T-helper 2 cell differentiation
GO:0045082 positive regulation of interleukin-10 biosynthetic process
GO:0045415 negative regulation of interleukin-8 biosynthetic process
GO:0045727 positive regulation of translation
GO:0045941 positive regulation of transcription
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048536 spleen development
GO:0051101 regulation of DNA binding
GO:0051457 maintenance of protein location in nucleus

Reference Sequence: NM_005178.2

10102bp CDS 1..5376

Homologous cDNA sequence in the JCRB Genebank

BCL3 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee
PtsC-13153