Gene Cluster: BCL2

Organism: Homo sapiens

Synonymous: Bcl-2

B-cell CLL/lymphoma 2

Map: 18q21.33|18q21.3

GO:0001836 release of cytochrome c from mitochondria
GO:0002020 protease binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006916 anti-apoptosis
GO:0006959 humoral immune response
GO:0007565 female pregnancy
GO:0008219 cell death
GO:0008284 positive regulation of cell proliferation
GO:0008633 activation of pro-apoptotic gene products
GO:0009314 response to radiation
GO:0009636 response to toxin
GO:0010039 response to iron ion
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0031069 hair follicle morphogenesis
GO:0031965 nuclear membrane
GO:0032848 negative regulation of cellular pH reduction
GO:0034097 response to cytokine stimulus
GO:0035094 response to nicotine
GO:0042100 B cell proliferation
GO:0042493 response to drug
GO:0042803 protein homodimerization activity
GO:0043473 pigmentation
GO:0043496 regulation of protein homodimerization activity
GO:0043497 regulation of protein heterodimerization activity
GO:0043524 negative regulation of neuron apoptosis
GO:0045069 regulation of viral genome replication
GO:0046902 regulation of mitochondrial membrane permeability
GO:0046982 protein heterodimerization activity
GO:0051434 BH3 domain binding
GO:0051607 defense response to virus
GO:0051881 regulation of mitochondrial membrane potential
GO:0051902 negative regulation of mitochondrial depolarization

Reference Sequence: NM_000633.2

6492bp CDS 494..1213

BCL2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee