Gene Cluster: PIGA

Organism: Homo sapiens

Synonymous: GPI3|PIG-A

phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria)

Link to Entrez Gene

Map: Xp22.1

GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005515 protein binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0009058 biosynthetic process
GO:0009893 positive regulation of metabolic process
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0016254 preassembly of GPI anchor in ER membrane
GO:0016757 transferase activity, transferring glycosyl groups
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity

Reference Sequence: NM_002641.1

3589bp CDS 86..1540

Homologous cDNA sequence in the JCRB Genebank

PIGA (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee
PflB8289 PflB8290