Gene Cluster: P2RX7

Organism: Homo sapiens

Synonymous: MGC20089|P2X7

purinergic receptor P2X, ligand-gated ion channel, 7

Map: 12q24

GO:0001530 lipopolysaccharide binding
GO:0001614 purinergic nucleotide receptor activity
GO:0002028 regulation of sodium ion transport
GO:0004872 receptor activity
GO:0004931 ATP-gated cation channel activity
GO:0005102 receptor binding
GO:0005216 ion channel activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral to plasma membrane
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007166 cell surface receptor linked signal transduction
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0019233 sensory perception of pain
GO:0030501 positive regulation of bone mineralization
GO:0032059 bleb
GO:0032060 bleb formation
GO:0033198 response to ATP
GO:0042803 protein homodimerization activity
GO:0042981 regulation of apoptosis
GO:0043409 negative regulation of MAPKKK cascade
GO:0045779 negative regulation of bone resorption
GO:0045919 positive regulation of cytolysis
GO:0046931 pore complex biogenesis
GO:0046982 protein heterodimerization activity
GO:0050718 positive regulation of interleukin-1 beta secretion
GO:0051495 positive regulation of cytoskeleton organization
GO:0051709 regulation of killing of cells of another organism
GO:0051899 membrane depolarization

Reference Sequence: NM_002562.4

3155bp CDS 97..1884

P2RX7 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee