Gene Cluster: SMAD2

Organism: Homo sapiens

Synonymous: JV18|JV18-1|MADH2|MADR2|MGC22139|MGC34440|hMAD-2|hSMAD2

SMAD family member 2

Link to Entrez Gene

Map: 18q21.1

GO:0001707 mesoderm formation
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006350 transcription
GO:0007242 intracellular signaling cascade
GO:0008134 transcription factor binding
GO:0009952 anterior/posterior pattern formation
GO:0016563 transcription activator activity
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0045165 cell fate commitment
GO:0045892 negative regulation of transcription, DNA-dependent
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048340 paraxial mesoderm morphogenesis
GO:0051098 regulation of binding

Reference Sequence: NM_005901.3

5415bp CDS 249..1652

Homologous cDNA sequence in the JCRB Genebank

SMAD2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)