Gene Cluster: EIF2AK1

Organism: Homo sapiens

Synonymous: HRI|KIAA1369

eukaryotic translation initiation factor 2-alpha kinase 1

Link to Entrez Gene

Map: 7p22

GO:0000166 nucleotide binding
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006950 response to stress
GO:0008285 negative regulation of cell proliferation
GO:0009605 response to external stimulus
GO:0016740 transferase activity
GO:0017148 negative regulation of translation
GO:0020037 heme binding
GO:0042803 protein homodimerization activity
GO:0045993 negative regulation of translational initiation by iron
GO:0046777 protein amino acid autophosphorylation
GO:0046986 negative regulation of hemoglobin biosynthetic process

Reference Sequence: NM_014413.2

2813bp CDS 63..1955

Homologous cDNA sequence in the JCRB Genebank

EIF2AK1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human
kaia1399_5EST
Chimpanzee
PflB4245