Gene Cluster: BACE1

Organism: Homo sapiens

Synonymous: ASP2|BACE|FLJ90568|HSPC104|KIAA1149

beta-site APP-cleaving enzyme 1

Link to Entrez Gene

Map: 11q23.2-q23.3

GO:0004190 aspartic-type endopeptidase activity
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005887 integral to plasma membrane
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0008233 peptidase activity
GO:0008798 beta-aspartyl-peptidase activity
GO:0016020 membrane
GO:0030424 axon
GO:0031410 cytoplasmic vesicle
GO:0050435 beta-amyloid metabolic process

Reference Sequence: NM_012104.3

5850bp CDS 462..1967

Homologous cDNA sequence in the JCRB Genebank

BACE1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee
PflB2341 PflB2341 PstA0855