Gene Cluster: EXT1

Organism: Homo sapiens

Synonymous: EXT|ttv

exostoses (multiple) 1

Link to Entrez Gene

Map: 8q24.11-q24.13

GO:0000139 Golgi membrane
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0005515 protein binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0006024 glycosaminoglycan biosynthetic process
GO:0007165 signal transduction
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0016757 transferase activity, transferring glycosyl groups
GO:0030176 integral to endoplasmic reticulum membrane
GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity
GO:0042803 protein homodimerization activity
GO:0045786 negative regulation of cell cycle
GO:0046982 protein heterodimerization activity
GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

Reference Sequence: NM_000127.2

3376bp CDS 774..3014

Homologous cDNA sequence in the JCRB Genebank

EXT1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee