Gene Cluster: DPYD

Organism: Homo sapiens

Synonymous: DHP|DPD|MGC132008|MGC70799

dihydropyrimidine dehydrogenase

Link to Entrez Gene

Map: 1p22

GO:0004158 dihydroorotate oxidase activity
GO:0004159 dihydrouracil dehydrogenase (NAD+) activity
GO:0005488 binding
GO:0005506 iron ion binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006145 purine base catabolic process
GO:0006207 `de novo` pyrimidine base biosynthetic process
GO:0006210 thymine catabolic process
GO:0006212 uracil catabolic process
GO:0006214 thymidine catabolic process
GO:0009055 electron carrier activity
GO:0016491 oxidoreductase activity
GO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0050660 FAD binding
GO:0050661 NADP binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0055114 oxidation reduction

Reference Sequence: NM_000110.2

4407bp CDS 102..3179

Homologous cDNA sequence in the JCRB Genebank

DPYD (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee