Gene Cluster: NOD1

Organism: Homo sapiens

Synonymous: CARD4|CLR7.1|NLRC1

nucleotide-binding oligomerization domain containing 1

Link to Entrez Gene

Map: 7p15-p14

GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0007242 intracellular signaling cascade
GO:0008656 caspase activator activity
GO:0016045 detection of bacterium
GO:0042228 interleukin-8 biosynthetic process
GO:0042742 defense response to bacterium
GO:0042834 peptidoglycan binding
GO:0042981 regulation of apoptosis
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051259 protein oligomerization

Reference Sequence: NM_006092.1

4390bp CDS 425..3286

Homologous cDNA sequence in the JCRB Genebank

NOD1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee
PflB4725