Gene Cluster: TRIB1

Organism: Homo sapiens

Synonymous: C8FW|GIG2|SKIP1

tribbles homolog 1 (Drosophila)

Link to Entrez Gene

Map: 8q24.13

GO:0004672 protein kinase activity
GO:0004860 protein kinase inhibitor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006468 protein amino acid phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0007254 JNK cascade
GO:0008134 transcription factor binding
GO:0014912 negative regulation of smooth muscle cell migration
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0043405 regulation of MAP kinase activity
GO:0043433 negative regulation of transcription factor activity
GO:0048662 negative regulation of smooth muscle cell proliferation

Reference Sequence: NM_025195.2

3658bp CDS 583..1701

Homologous cDNA sequence in the JCRB Genebank

TRIB1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee