Gene Cluster: ADAM10

Organism: Homo sapiens

Synonymous: CD156c|HsT18717|MADM|kuz

ADAM metallopeptidase domain 10

Map: 15q2|15q22

GO:0001701 in utero embryonic development
GO:0004222 metalloendopeptidase activity
GO:0005178 integrin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005798 Golgi-associated vesicle
GO:0005886 plasma membrane
GO:0006468 protein amino acid phosphorylation
GO:0006508 proteolysis
GO:0007162 negative regulation of cell adhesion
GO:0007219 Notch signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007267 cell-cell signaling
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
GO:0009986 cell surface
GO:0012505 endomembrane system
GO:0016021 integral to membrane
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0051089 constitutive protein ectodomain proteolysis

Reference Sequence: NM_001110.2

3927bp CDS 445..2691

ADAM10 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee