Gene Cluster: MED12

Organism: Homo sapiens

Synonymous: CAGH45|HOPA|KIAA0192|OPA1|TNRC11|TRAP230

mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)

Link to Entrez Gene

Map: Xq13

GO:0000119 mediator complex
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005813 centrosome
GO:0006350 transcription
GO:0006355 regulation of transcription, DNA-dependent
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0016455 RNA polymerase II transcription mediator activity
GO:0019904 protein domain specific binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
GO:0030521 androgen receptor signaling pathway
GO:0042809 vitamin D receptor binding
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046966 thyroid hormone receptor binding

Reference Sequence: NM_005120.1

6757bp CDS 40..6678

Homologous cDNA sequence in the JCRB Genebank

MED12 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee