Gene Cluster: CD74

Organism: Homo sapiens

Synonymous: DHLAG|HLADG|Ia-GAMMA|protein 41

CD74 molecule, major histocompatibility complex, class II invariant chain

Link to Entrez Gene

Map: 5q32

GO:0001516 prostaglandin biosynthetic process
GO:0005622 intracellular
GO:0006461 protein complex assembly
GO:0006886 intracellular protein transport
GO:0006955 immune response
GO:0007165 signal transduction
GO:0008283 cell proliferation
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0016064 immunoglobulin mediated immune response
GO:0019882 antigen processing and presentation
GO:0019883 antigen processing and presentation of endogenous antigen
GO:0019955 cytokine binding
GO:0042289 MHC class II protein binding
GO:0042802 identical protein binding
GO:0043030 regulation of macrophage activation
GO:0043066 negative regulation of apoptosis
GO:0045058 T cell selection

Reference Sequence: NM_001025159.1

1519bp CDS 12..902

Homologous cDNA sequence in the JCRB Genebank

CD74 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human
3NHC1954_5EST 3NHC2167_5EST 3NHC2316_5EST 3NHC2455_5EST L12434_5EST kaia0771_5EST kaia1384_5EST kaia2234_5EST kaia4311_5EST
Chimpanzee
PccB1029 PccB1793 PccB2035 PccB2118 PccB2471 PccB3401 PccB3953 PccB4143 PflB0122 PflB0461 PflB0736 PflB0834 PflB1251 PflB3443 PflB3536 PflB3654 PflB4805 PflB5303 PflB5946 PflB6768 PflB7243 PflB8505 PflB8765 PflB8859 PflB8916 PflB8933 PflB9105 PflB9708 PorA0004 PorA0402 PorA0474 PorA0593 PorA0593 PorA0593 PorA0687 PorA0783 PorA0833 PorA0980 PorA1277 PorB0367 PorB0601 PorB0643 PorB0662 PorB0710 PorB0758 PorB0895 PorB1145 PorB1351 PorB1433 PorB1474 PorB1532 PstA2537 PstA2586 PstA2791 PstA5944 PstA7308