Gene Cluster: TNFRSF10A

Organism: Homo sapiens

Synonymous: APO2|CD261|DR4|MGC9365|TRAILR-1|TRAILR1

tumor necrosis factor receptor superfamily, member 10a

Link to Entrez Gene

Map: 8p21

GO:0004872 receptor activity
GO:0005035 death receptor activity
GO:0006915 apoptosis
GO:0006917 induction of apoptosis
GO:0006919 caspase activation
GO:0007165 signal transduction
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0008625 induction of apoptosis via death domain receptors
GO:0008656 caspase activator activity
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0045569 TRAIL binding

Reference Sequence: NM_003844.2

1723bp CDS 66..1472

Homologous cDNA sequence in the JCRB Genebank

TNFRSF10A (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee