Gene Cluster: RIPK2

Organism: Homo sapiens

Synonymous: CARD3|CARDIAK|CCK|GIG30|RICK|RIP2

receptor-interacting serine-threonine kinase 2

Link to Entrez Gene

Map: 8q21

GO:0000166 nucleotide binding
GO:0004674 protein serine/threonine kinase activity
GO:0004871 signal transducer activity
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein amino acid phosphorylation
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0030274 LIM domain binding
GO:0042098 T cell proliferation
GO:0043065 positive regulation of apoptosis
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050700 CARD domain binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity

Reference Sequence: NM_003821.5

2588bp CDS 315..1937

Homologous cDNA sequence in the JCRB Genebank

RIPK2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee