Gene Cluster: TNFSF10

Organism: Homo sapiens

Synonymous: APO2L|Apo-2L|CD253|TL2|TRAIL

tumor necrosis factor (ligand) superfamily, member 10

Link to Entrez Gene

Map: 3q26

GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005625 soluble fraction
GO:0005887 integral to plasma membrane
GO:0006915 apoptosis
GO:0006917 induction of apoptosis
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008270 zinc ion binding
GO:0008633 activation of pro-apoptotic gene products
GO:0016020 membrane
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046872 metal ion binding

Reference Sequence: NM_003810.2

1776bp CDS 96..941

Homologous cDNA sequence in the JCRB Genebank

TNFSF10 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee