Gene Cluster: RUNX2

Organism: Homo sapiens

Synonymous: AML3|CBFA1|CCD|CCD1|MGC120022|MGC120023|OSF2|PEA2aA|PEBP2A1|PEBP2A2|PEBP2aA|PEBP2aA1

runt-related transcription factor 2

Link to Entrez Gene

Map: 6p21

GO:0001501 skeletal system development
GO:0001649 osteoblast differentiation
GO:0002062 chondrocyte differentiation
GO:0003682 chromatin binding
GO:0003700 transcription factor activity
GO:0003702 RNA polymerase II transcription factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-dependent
GO:0008284 positive regulation of cell proliferation
GO:0016481 negative regulation of transcription
GO:0016563 transcription activator activity
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
GO:0042487 regulation of odontogenesis of dentine-containing tooth
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048469 cell maturation

Reference Sequence: NM_004348.3

5720bp CDS 401..1924

Homologous cDNA sequence in the JCRB Genebank

RUNX2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee