Gene Cluster: MADD

Organism: Homo sapiens

Synonymous: DENN|IG20|KIAA0358|RAB3GEP

MAP-kinase activating death domain

Link to Entrez Gene

Map: 11p11.2

GO:0000187 activation of MAPK activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005123 death receptor binding
GO:0005515 protein binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007166 cell surface receptor linked signal transduction
GO:0016021 integral to membrane
GO:0017112 Rab guanyl-nucleotide exchange factor activity
GO:0030295 protein kinase activator activity
GO:0042981 regulation of apoptosis
GO:0051726 regulation of cell cycle

Reference Sequence: NM_003682.2

6016bp CDS 192..5135

Homologous cDNA sequence in the JCRB Genebank

MADD (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human
3NHC0721_5EST
Chimpanzee
PflB7118