Gene Cluster: CASP3

Organism: Homo sapiens

Synonymous: CPP32|CPP32B|SCA-1

caspase 3, apoptosis-related cysteine peptidase

Map: 4q34

GO:0001782 B cell homeostasis
GO:0001836 release of cytochrome c from mitochondria
GO:0004197 cysteine-type endopeptidase activity
GO:0004861 cyclin-dependent protein kinase inhibitor activity
GO:0005515 protein binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006309 DNA fragmentation during apoptosis
GO:0006508 proteolysis
GO:0006915 apoptosis
GO:0006917 induction of apoptosis
GO:0007507 heart development
GO:0007605 sensory perception of sound
GO:0008233 peptidase activity
GO:0008625 induction of apoptosis via death domain receptors
GO:0008631 induction of apoptosis by oxidative stress
GO:0009411 response to UV
GO:0009611 response to wounding
GO:0030216 keratinocyte differentiation
GO:0030264 nuclear fragmentation during apoptosis
GO:0030889 negative regulation of B cell proliferation
GO:0043029 T cell homeostasis
GO:0043066 negative regulation of apoptosis
GO:0045165 cell fate commitment
GO:0045736 negative regulation of cyclin-dependent protein kinase activity
GO:0046007 negative regulation of activated T cell proliferation
GO:0051402 neuron apoptosis

Reference Sequence: NM_004346.3

2689bp CDS 264..1097

CASP3 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee