Gene Cluster: CXCR4

Organism: Homo sapiens

Synonymous: CD184|D2S201E|FB22|HM89|HSY3RR|LAP3|LCR1|LESTR|NPY3R|NPYR|NPYRL|NPYY3R|WHIM

chemokine (C-X-C motif) receptor 4

Link to Entrez Gene

Map: 2q21

GO:0000187 activation of MAPK activity
GO:0001569 patterning of blood vessels
GO:0001666 response to hypoxia
GO:0001667 ameboidal cell migration
GO:0001764 neuron migration
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral to plasma membrane
GO:0006915 apoptosis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor protein signaling pathway
GO:0007204 elevation of cytosolic calcium ion concentration
GO:0007281 germ cell development
GO:0007420 brain development
GO:0008045 motor axon guidance
GO:0008354 germ cell migration
GO:0009615 response to virus
GO:0015026 coreceptor activity
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019059 initiation of viral infection
GO:0030334 regulation of cell migration
GO:0030426 growth cone
GO:0031252 cell leading edge
GO:0032027 myosin light chain binding
GO:0042098 T cell proliferation
GO:0044419 interspecies interaction between organisms

Reference Sequence: NM_001008540.1

1912bp CDS 305..1375

Homologous cDNA sequence in the JCRB Genebank

CXCR4 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee