Gene Cluster: TOP2B

Organism: Homo sapiens

Synonymous: TOPIIB|top2beta

topoisomerase (DNA) II beta 180kDa

Link to Entrez Gene

Map: 3p24

GO:0000166 nucleotide binding
GO:0000792 heterochromatin
GO:0001764 neuron migration
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006265 DNA topological change
GO:0007409 axonogenesis
GO:0008022 protein C-terminus binding
GO:0030900 forebrain development
GO:0042826 histone deacetylase binding
GO:0046982 protein heterodimerization activity

Reference Sequence: NM_001068.2

5189bp CDS 1..4866

Homologous cDNA sequence in the JCRB Genebank

TOP2B (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee