Gene Cluster: STAT3

Organism: Homo sapiens

Synonymous: APRF|FLJ20882|MGC16063

signal transducer and activator of transcription 3 (acute-phase response factor)

Link to Entrez Gene

Map: 17q21.31

GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0003700 transcription factor activity
GO:0004871 signal transducer activity
GO:0005062 hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-dependent
GO:0006928 cell motion
GO:0007165 signal transduction
GO:0007259 JAK-STAT cascade
GO:0007399 nervous system development
GO:0008134 transcription factor binding
GO:0019221 cytokine-mediated signaling pathway
GO:0044419 interspecies interaction between organisms

Reference Sequence: NM_139276.2

4978bp CDS 241..2553

Homologous cDNA sequence in the JCRB Genebank

STAT3 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee