Gene Cluster: BPI

Organism: Homo sapiens

bactericidal/permeability-increasing protein

Link to Entrez Gene

Map: 20q11.23-q12

GO:0001530 lipopolysaccharide binding
GO:0005737 cytoplasm
GO:0005887 integral to plasma membrane
GO:0008289 lipid binding
GO:0016020 membrane
GO:0032715 negative regulation of interleukin-6 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0042742 defense response to bacterium
GO:0043031 negative regulation of macrophage activation

Reference Sequence: NM_001725.1

1813bp CDS 31..1494

Homologous cDNA sequence in the JCRB Genebank

BPI (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee