Gene Cluster: BMPR2

Organism: Homo sapiens

Synonymous: BMPR-II|BMPR3|BMR2|BRK-3|PPH1|T-ALK

bone morphogenetic protein receptor, type II (serine/threonine kinase)

Link to Entrez Gene

Map: 2q33-q34

GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0001707 mesoderm formation
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004872 receptor activity
GO:0005024 transforming growth factor beta receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral to plasma membrane
GO:0006366 transcription from RNA polymerase II promoter
GO:0006468 protein amino acid phosphorylation
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0009952 anterior/posterior pattern formation
GO:0009986 cell surface
GO:0014916 regulation of lung blood pressure
GO:0016020 membrane
GO:0016740 transferase activity
GO:0030145 manganese ion binding
GO:0030501 positive regulation of bone mineralization
GO:0030509 BMP signaling pathway
GO:0042127 regulation of cell proliferation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045906 negative regulation of vasoconstriction
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048286 alveolus development

Reference Sequence: NM_001204.5

11449bp CDS 528..3644

Homologous cDNA sequence in the JCRB Genebank

BMPR2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee