Gene Cluster: PTK2

Organism: Homo sapiens

Synonymous: FADK|FAK|FAK1|pp125FAK

PTK2 protein tyrosine kinase 2

Link to Entrez Gene

Map: 8q24-qter

GO:0000166 nucleotide binding
GO:0000226 microtubule cytoskeleton organization
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0001764 neuron migration
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006468 protein amino acid phosphorylation
GO:0007172 signal complex assembly
GO:0007229 integrin-mediated signaling pathway
GO:0016324 apical plasma membrane
GO:0016740 transferase activity
GO:0021955 central nervous system neuron axonogenesis
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030198 extracellular matrix organization
GO:0040023 establishment of nucleus localization
GO:0042169 SH2 domain binding
GO:0043542 endothelial cell migration
GO:0046621 negative regulation of organ growth
GO:0046777 protein amino acid autophosphorylation
GO:0050771 negative regulation of axonogenesis
GO:0051964 negative regulation of synaptogenesis

Reference Sequence: NM_153831.2

4453bp CDS 231..3389

Homologous cDNA sequence in the JCRB Genebank

PTK2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee