Gene Cluster: PTGS2

Organism: Homo sapiens

Synonymous: COX-2|COX2|PGG/HS|PGHS-2|PHS-2|hCox-2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Link to Entrez Gene

Map: 1q25.2-q25.3

GO:0004601 peroxidase activity
GO:0004666 prostaglandin-endoperoxide synthase activity
GO:0005506 iron ion binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005792 microsome
GO:0006633 fatty acid biosynthetic process
GO:0006928 cell motion
GO:0006979 response to oxidative stress
GO:0008217 regulation of blood pressure
GO:0016020 membrane
GO:0016491 oxidoreductase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019371 cyclooxygenase pathway
GO:0020037 heme binding
GO:0042640 anagen
GO:0046872 metal ion binding
GO:0050727 regulation of inflammatory response
GO:0055114 oxidation reduction

Reference Sequence: NM_000963.1

4465bp CDS 135..1949

Homologous cDNA sequence in the JCRB Genebank

PTGS2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee