Gene Cluster: PRNP

Organism: Homo sapiens

Synonymous: ASCR|CD230|CJD|GSS|MGC26679|PRIP|PrP|PrP27-30|PrP33-35C|PrPc

prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)

Link to Entrez Gene

Map: 20p13

GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006878 cellular copper ion homeostasis
GO:0006979 response to oxidative stress
GO:0008017 microtubule binding
GO:0008152 metabolic process
GO:0016020 membrane
GO:0019898 extrinsic to membrane
GO:0031225 anchored to membrane
GO:0042802 identical protein binding
GO:0045121 membrane raft
GO:0051260 protein homooligomerization

Reference Sequence: NM_000311.2

2483bp CDS 101..862

Homologous cDNA sequence in the JCRB Genebank

PRNP (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee
PflB0281 PflB0282 PflB0608 PflB0608 PflB0872 PflB1172 PflB1184 PflB1349 PflB1349 PflB1557 PflB1557 PflB1595 PflB1681 PflB1681 PflB1705 PflB1705 PflB1724 PflB1724 PflB1930 PflB2187 PflB2189 PflB3810 PflB3810 PflB3825 PflB3825 PflB4319 PflB4789 PflB5640 PflB6163 PflB7718 PflB7890 PflB8159 PflB8915 PflB9124 PflB9124 PorA0468 PorA1179 PorA1179 PorB0502