Gene Cluster: PPT1

Organism: Homo sapiens

Synonymous: CLN1|INCL|PPT

palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)

Map: 1p32

GO:0002084 protein depalmitoylation
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005624 membrane fraction
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006309 DNA fragmentation during apoptosis
GO:0006464 protein modification process
GO:0007042 lysosomal lumen acidification
GO:0007269 neurotransmitter secretion
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007601 visual perception
GO:0007625 grooming behavior
GO:0008021 synaptic vesicle
GO:0008306 associative learning
GO:0008344 adult locomotory behavior
GO:0008474 palmitoyl-(protein) hydrolase activity
GO:0015031 protein transport
GO:0016042 lipid catabolic process
GO:0016290 palmitoyl-CoA hydrolase activity
GO:0016787 hydrolase activity
GO:0030149 sphingolipid catabolic process
GO:0030308 negative regulation of cell growth
GO:0030424 axon
GO:0030425 dendrite
GO:0031579 membrane raft organization
GO:0032429 regulation of phospholipase A2 activity
GO:0043025 cell soma
GO:0043524 negative regulation of neuron apoptosis
GO:0044257 cellular protein catabolic process
GO:0045121 membrane raft
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0048549 positive regulation of pinocytosis
GO:0048666 neuron development
GO:0050803 regulation of synapse structure and activity
GO:0050896 response to stimulus
GO:0051181 cofactor transport
GO:0051186 cofactor metabolic process

Reference Sequence: NM_000310.2

2358bp CDS 59..979

PPT1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee