Gene Cluster: PKD2

Organism: Homo sapiens

Synonymous: APKD2|MGC138466|MGC138468|PC2|PKD4

polycystic kidney disease 2 (autosomal dominant)

Link to Entrez Gene

Map: 4q21-q23

GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0005932 basal body
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0007050 cell cycle arrest
GO:0007160 cell-matrix adhesion
GO:0007259 JAK-STAT cascade
GO:0007368 determination of left/right symmetry
GO:0008022 protein C-terminus binding
GO:0008092 cytoskeletal protein binding
GO:0009887 organ morphogenesis
GO:0015629 actin cytoskeleton
GO:0016021 integral to membrane
GO:0050982 detection of mechanical stimulus

Reference Sequence: NM_000297.2

5073bp CDS 67..2973

Homologous cDNA sequence in the JCRB Genebank

PKD2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee