Gene Cluster: PIK3R1

Organism: Homo sapiens

Synonymous: GRB1|p85-ALPHA

phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)

Link to Entrez Gene

Map: 5q13.1

GO:0005158 insulin receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005545 phosphatidylinositol binding
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005943 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex
GO:0007242 intracellular signaling cascade
GO:0008286 insulin receptor signaling pathway
GO:0019903 protein phosphatase binding
GO:0035014 phosphoinositide 3-kinase regulator activity
GO:0043125 ErbB-3 class receptor binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding
GO:0044419 interspecies interaction between organisms
GO:0046854 phosphoinositide phosphorylation
GO:0048009 insulin-like growth factor receptor signaling pathway

Reference Sequence: NM_181523.1

6453bp CDS 43..2217

Homologous cDNA sequence in the JCRB Genebank

PIK3R1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee