Gene Cluster: PLCE1

Organism: Homo sapiens

Synonymous: FLJ23659|KIAA1516|NPHS3|PLCE

phospholipase C, epsilon 1

Map: 10q23

GO:0000139 Golgi membrane
GO:0000187 activation of MAPK activity
GO:0001558 regulation of cell growth
GO:0004435 phosphoinositide phospholipase C activity
GO:0004871 signal transducer activity
GO:0005057 receptor signaling protein activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005622 intracellular
GO:0005624 membrane fraction
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006629 lipid metabolic process
GO:0006644 phospholipid metabolic process
GO:0006651 diacylglycerol biosynthetic process
GO:0006940 regulation of smooth muscle contraction
GO:0007010 cytoskeleton organization
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007204 elevation of cytosolic calcium ion concentration
GO:0007205 activation of protein kinase C activity
GO:0007264 small GTPase mediated signal transduction
GO:0007507 heart development
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0008283 cell proliferation
GO:0016042 lipid catabolic process
GO:0016787 hydrolase activity
GO:0017016 Ras GTPase binding
GO:0019722 calcium-mediated signaling
GO:0019899 enzyme binding
GO:0032835 glomerulus development
GO:0045859 regulation of protein kinase activity
GO:0046578 regulation of Ras protein signal transduction
GO:0048016 inositol phosphate-mediated signaling

Reference Sequence: NM_016341.2

7609bp CDS 236..7147

PLCE1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee