Gene Cluster: PAFAH1B1

Organism: Homo sapiens

Synonymous: LIS1|LIS2|MDCR|MDS|PAFAH

platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa

Map: 17p13.3

GO:0000132 establishment of mitotic spindle orientation
GO:0000226 microtubule cytoskeleton organization
GO:0000235 astral microtubule
GO:0000776 kinetochore
GO:0001675 acrosome formation
GO:0001764 neuron migration
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0005938 cell cortex
GO:0006810 transport
GO:0007049 cell cycle
GO:0007067 mitosis
GO:0007268 synaptic transmission
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0007405 neuroblast proliferation
GO:0007611 learning or memory
GO:0008017 microtubule binding
GO:0008090 retrograde axon cargo transport
GO:0008201 heparin binding
GO:0008344 adult locomotory behavior
GO:0016020 membrane
GO:0016042 lipid catabolic process
GO:0021540 corpus callosum morphogenesis
GO:0021766 hippocampus development
GO:0021819 layer formation in the cerebral cortex
GO:0021987 cerebral cortex development
GO:0030036 actin cytoskeleton organization
GO:0030154 cell differentiation
GO:0031252 cell leading edge
GO:0031512 motile primary cilium
GO:0031513 nonmotile primary cilium
GO:0031965 nuclear membrane
GO:0032319 regulation of Rho GTPase activity
GO:0034452 dynactin binding
GO:0042803 protein homodimerization activity
GO:0043274 phospholipase binding
GO:0045502 dynein binding
GO:0046469 platelet activating factor metabolic process
GO:0047496 vesicle transport along microtubule
GO:0048471 perinuclear region of cytoplasm
GO:0048854 brain morphogenesis
GO:0050885 neuromuscular process controlling balance
GO:0051219 phosphoprotein binding
GO:0051301 cell division

Reference Sequence: NM_000430.2

5581bp CDS 556..1788

Homologous cDNA sequence in the JCRB Genebank

PAFAH1B1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee