Gene Cluster: NPM1

Organism: Homo sapiens

Synonymous: B23|MGC104254|NPM

nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Link to Entrez Gene

Map: 5q35

GO:0003676 nucleic acid binding
GO:0003713 transcription coactivator activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0006916 anti-apoptosis
GO:0006950 response to stress
GO:0007098 centrosome cycle
GO:0007165 signal transduction
GO:0007569 cell aging
GO:0008285 negative regulation of cell proliferation
GO:0030957 Tat protein binding
GO:0042255 ribosome assembly
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
GO:0051059 NF-kappaB binding
GO:0051082 unfolded protein binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity

Reference Sequence: NM_002520.5

1373bp CDS 156..1040

Homologous cDNA sequence in the JCRB Genebank

NPM1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee