Gene Cluster: LDLR

Organism: Homo sapiens

Synonymous: FH|FHC

low density lipoprotein receptor (familial hypercholesterolemia)

Link to Entrez Gene

Map: 19p13.3

GO:0004872 receptor activity
GO:0004888 transmembrane receptor activity
GO:0005041 low-density lipoprotein receptor activity
GO:0005319 lipid transporter activity
GO:0005509 calcium ion binding
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005887 integral to plasma membrane
GO:0005905 coated pit
GO:0006493 protein amino acid O-linked glycosylation
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0006897 endocytosis
GO:0008034 lipoprotein binding
GO:0008202 steroid metabolic process
GO:0008203 cholesterol metabolic process
GO:0010008 endosome membrane
GO:0030229 very-low-density lipoprotein receptor activity
GO:0030299 cholesterol absorption
GO:0030301 cholesterol transport
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0034383 low-density lipoprotein particle clearance
GO:0042632 cholesterol homeostasis
GO:0044419 interspecies interaction between organisms

Reference Sequence: NM_000527.2

5175bp CDS 94..2676

Homologous cDNA sequence in the JCRB Genebank

LDLR (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee