Gene Cluster: HSPD1

Organism: Homo sapiens

Synonymous: CPN60|GROEL|HSP60|HSP65|HuCHA60|SPG13

heat shock 60kDa protein 1 (chaperonin)

Link to Entrez Gene

Map: 2q33.1

GO:0000166 nucleotide binding
GO:0001530 lipopolysaccharide binding
GO:0002039 p53 binding
GO:0002368 B cell cytokine production
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0002842 positive regulation of T cell mediated immune response to tumor cell
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005905 coated pit
GO:0006919 caspase activation
GO:0006986 response to unfolded protein
GO:0009986 cell surface
GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0030135 coated vesicle
GO:0032727 positive regulation of interferon-alpha production
GO:0032729 positive regulation of interferon-gamma production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032755 positive regulation of interleukin-6 production
GO:0042026 protein refolding
GO:0042100 B cell proliferation
GO:0043032 positive regulation of macrophage activation
GO:0043065 positive regulation of apoptosis
GO:0043066 negative regulation of apoptosis
GO:0043498 cell surface binding
GO:0044419 interspecies interaction between organisms
GO:0046696 lipopolysaccharide receptor complex
GO:0048291 isotype switching to IgG isotypes
GO:0050821 protein stabilization
GO:0050870 positive regulation of T cell activation
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding

Reference Sequence: NM_002156.4

2339bp CDS 138..1859

Homologous cDNA sequence in the JCRB Genebank

HSPD1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human
HDG0492 w00750_5EST
Chimpanzee
PorB1158 PtsC-14522 PtsC-16153