Gene Cluster: APC

Organism: Homo sapiens

Synonymous: DP2|DP2.5|DP3|FAP|FPC|GS

adenomatosis polyposis coli

Map: 5q21-q22

GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006461 protein complex assembly
GO:0006974 response to DNA damage stimulus
GO:0007026 negative regulation of microtubule depolymerization
GO:0007050 cell cycle arrest
GO:0007155 cell adhesion
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding
GO:0008285 negative regulation of cell proliferation
GO:0008605 protein kinase CK2 regulator activity
GO:0009798 axis specification
GO:0009952 anterior/posterior pattern formation
GO:0009953 dorsal/ventral pattern formation
GO:0016328 lateral plasma membrane
GO:0019901 protein kinase binding
GO:0030877 beta-catenin destruction complex
GO:0045736 negative regulation of cyclin-dependent protein kinase activity
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
GO:0060070 Wnt receptor signaling pathway through beta-catenin

Reference Sequence: NM_000038.3

10719bp CDS 58..8589

APC (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee