Gene Cluster: GPX4

Organism: Homo sapiens

Synonymous: MCSP|PHGPx|snGPx|snPHGPx

glutathione peroxidase 4 (phospholipid hydroperoxidase)

Link to Entrez Gene

Map: 19p13.3

GO:0004602 glutathione peroxidase activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
GO:0006325 establishment or maintenance of chromatin architecture
GO:0006644 phospholipid metabolic process
GO:0006979 response to oxidative stress
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0008430 selenium binding
GO:0016491 oxidoreductase activity
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity
GO:0055114 oxidation reduction

Reference Sequence: NM_001039848.1

1031bp CDS 86..790

Homologous cDNA sequence in the JCRB Genebank

GPX4 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee
PflB1651 PflB2976 PflB5134