Gene Cluster: GPX1

Organism: Homo sapiens

Synonymous: GSHPX1|MGC14399|MGC88245

glutathione peroxidase 1

Link to Entrez Gene

Map: 3p21.3

GO:0001836 release of cytochrome c from mitochondria
GO:0004602 glutathione peroxidase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006749 glutathione metabolic process
GO:0006916 anti-apoptosis
GO:0006979 response to oxidative stress
GO:0008430 selenium binding
GO:0008539 proteasome inhibitor activity
GO:0008631 induction of apoptosis by oxidative stress
GO:0009650 UV protection
GO:0010269 response to selenium ion
GO:0016491 oxidoreductase activity
GO:0017124 SH3 domain binding
GO:0033599 regulation of mammary gland epithelial cell proliferation
GO:0040029 regulation of gene expression, epigenetic
GO:0042744 hydrogen peroxide catabolic process
GO:0043154 negative regulation of caspase activity
GO:0043295 glutathione binding
GO:0055114 oxidation reduction
GO:0060047 heart contraction

Reference Sequence: NM_201397.1

1200bp CDS 81..377

Homologous cDNA sequence in the JCRB Genebank

GPX1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human
ColF3444_5EST ColF4152_5EST ColF4152_5EST kaia4137_5EST kaia4137_5EST
Chimpanzee
PccB0268 PccB0268 PccB1256 PccB1256 PccB3346 PflB3550 PflB5874 PflB8968 PorA0030 PorA0030 PorB0906