Gene Cluster: HTRA2

Organism: Homo sapiens

Synonymous: OMI|PARK13|PRSS25

HtrA serine peptidase 2

Link to Entrez Gene

Map: 2p12

GO:0004252 serine-type endopeptidase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006508 proteolysis
GO:0006915 apoptosis
GO:0006950 response to stress
GO:0007005 mitochondrion organization
GO:0007628 adult walking behavior
GO:0008233 peptidase activity
GO:0008629 induction of apoptosis by intracellular signals
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0030900 forebrain development
GO:0031966 mitochondrial membrane
GO:0040014 regulation of multicellular organism growth
GO:0048666 neuron development
GO:0051082 unfolded protein binding

Reference Sequence: NM_013247.4

2550bp CDS 603..1979

Homologous cDNA sequence in the JCRB Genebank

HTRA2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee