Gene Cluster: GCLM

Organism: Homo sapiens

Synonymous: GLCLR

glutamate-cysteine ligase, modifier subunit

Link to Entrez Gene

Map: 1p22.1

GO:0004357 glutamate-cysteine ligase activity
GO:0005515 protein binding
GO:0005625 soluble fraction
GO:0005829 cytosol
GO:0006534 cysteine metabolic process
GO:0006536 glutamate metabolic process
GO:0006750 glutathione biosynthetic process
GO:0006979 response to oxidative stress
GO:0016491 oxidoreductase activity
GO:0017109 glutamate-cysteine ligase complex
GO:0035226 glutamate-cysteine ligase catalytic subunit binding
GO:0035229 positive regulation of glutamate-cysteine ligase activity
GO:0042493 response to drug
GO:0043066 negative regulation of apoptosis
GO:0046982 protein heterodimerization activity
GO:0050880 regulation of blood vessel size
GO:0051900 regulation of mitochondrial depolarization

Reference Sequence: NM_002061.2

3074bp CDS 294..1118

Homologous cDNA sequence in the JCRB Genebank

GCLM (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee