Gene Cluster: SIRT3

Organism: Homo sapiens

Synonymous: SIR2L3

sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)

Link to Entrez Gene

Map: 11p15.5

GO:0003677 DNA binding
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005677 chromatin silencing complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006342 chromatin silencing
GO:0006355 regulation of transcription, DNA-dependent
GO:0006471 protein amino acid ADP-ribosylation
GO:0006476 protein amino acid deacetylation
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0016787 hydrolase activity
GO:0017136 NAD-dependent histone deacetylase activity
GO:0046872 metal ion binding
GO:0051287 NAD binding

Reference Sequence: NM_012239.4

2900bp CDS 34..1233

Homologous cDNA sequence in the JCRB Genebank

SIRT3 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee