Gene Cluster: FLT1

Organism: Homo sapiens

Synonymous: FLT|VEGFR1

fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

Link to Entrez Gene

Map: 13q12

GO:0000166 nucleotide binding
GO:0001569 patterning of blood vessels
GO:0004872 receptor activity
GO:0005021 vascular endothelial growth factor receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral to plasma membrane
GO:0006468 protein amino acid phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organismal development
GO:0007565 female pregnancy
GO:0008284 positive regulation of cell proliferation
GO:0016477 cell migration
GO:0016740 transferase activity
GO:0019838 growth factor binding
GO:0030154 cell differentiation
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0042802 identical protein binding

Reference Sequence: NM_002019.2

5777bp CDS 250..4266

Homologous cDNA sequence in the JCRB Genebank

FLT1 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee