Gene Cluster: SIRT2

Organism: Homo sapiens

Synonymous: SIR2L|SIR2L2

sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)

Map: 19q13

GO:0000183 chromatin silencing at rDNA
GO:0003677 DNA binding
GO:0005677 chromatin silencing complex
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0006348 chromatin silencing at telomere
GO:0006355 regulation of transcription, DNA-dependent
GO:0006471 protein amino acid ADP-ribosylation
GO:0006980 redox signal response
GO:0007049 cell cycle
GO:0007067 mitosis
GO:0007096 regulation of exit from mitosis
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0016481 negative regulation of transcription
GO:0016575 histone deacetylation
GO:0016787 hydrolase activity
GO:0017136 NAD-dependent histone deacetylase activity
GO:0035035 histone acetyltransferase binding
GO:0042325 regulation of phosphorylation
GO:0042826 histone deacetylase binding
GO:0042903 tubulin deacetylase activity
GO:0043130 ubiquitin binding
GO:0045843 negative regulation of striated muscle development
GO:0046872 metal ion binding
GO:0051287 NAD binding
GO:0051301 cell division

Reference Sequence: NM_012237.2

1963bp CDS 201..1370

SIRT2 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee