Gene Cluster: ERCC3

Organism: Homo sapiens

Synonymous: BTF2|GTF2H|RAD25|TFIIH|XPB

excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

Link to Entrez Gene

Map: 2q21

GO:0000075 cell cycle checkpoint
GO:0000166 nucleotide binding
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0000718 nucleotide-excision repair, DNA damage removal
GO:0003684 damaged DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005675 holo TFIIH complex
GO:0006265 DNA topological change
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006350 transcription
GO:0006355 regulation of transcription, DNA-dependent
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 RNA elongation from RNA polymerase II promoter
GO:0006917 induction of apoptosis
GO:0006979 response to oxidative stress
GO:0007605 sensory perception of sound
GO:0008022 protein C-terminus binding
GO:0008104 protein localization
GO:0008134 transcription factor binding
GO:0009650 UV protection
GO:0016787 hydrolase activity
GO:0016887 ATPase activity
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035315 hair cell differentiation
GO:0043138 3`-5` DNA helicase activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0047485 protein N-terminus binding

Reference Sequence: NM_000122.1

2751bp CDS 96..2444

Homologous cDNA sequence in the JCRB Genebank

ERCC3 (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Human

Chimpanzee