Gene Cluster: PRKCA

Organism: Homo sapiens

Synonymous: AAG6|MGC129900|MGC129901|PKC-alpha|PKCA|PRKACA

protein kinase C, alpha

Link to Entrez Gene

Map: 17q22-q23.2

GO:0000166 nucleotide binding
GO:0000188 inactivation of MAPK activity
GO:0001933 negative regulation of protein amino acid phosphorylation
GO:0001934 positive regulation of protein amino acid phosphorylation
GO:0002026 regulation of the force of heart contraction
GO:0002062 chondrocyte differentiation
GO:0004698 calcium-dependent protein kinase C activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005624 membrane fraction
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006469 negative regulation of protein kinase activity
GO:0006874 cellular calcium ion homeostasis
GO:0006937 regulation of muscle contraction
GO:0007242 intracellular signaling cascade
GO:0008270 zinc ion binding
GO:0008624 induction of apoptosis by extracellular signals
GO:0008629 induction of apoptosis by intracellular signals
GO:0016740 transferase activity
GO:0019992 diacylglycerol binding
GO:0030593 neutrophil chemotaxis
GO:0046325 negative regulation of glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046872 metal ion binding
GO:0050729 positive regulation of inflammatory response
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050930 induction of positive chemotaxis

Reference Sequence: NM_002737.2

8787bp CDS 45..2063

Homologous cDNA sequence in the JCRB Genebank

PRKCA (5:5'UTR, C:CDS, 3:3'UTR, N:Unknown)

Chimpanzee